EpiSort: Enumeration of cell types using targeted bisulfite sequencing


The cellular composition of tumors is now recognized as an essential phenotype, with implications to diagnostic, progression and therapy efficacy. A tool for accurate profiling of the tumor microenvironment is lacking, as single-cell methods and computational approaches are not applicable or suffer from low accuracy. Here we present EpiSort, a novel strategy based on targeted bisulfite sequencing, which allows the accurate enumeration of 23 cell types and may be applicable to cancer studies.

Dvir Aran
Dvir Aran

Computational Biologist, analyzing single-cell RNA-seq and clinical data in cancer and other diseases.